Opinion from a Libertarian ViewPoint

Posts Tagged ‘Antibody Testing’

Erie Times E-Edition Article-Antibody testing can’t confirm if you have COVID protection

Posted by M. C. on September 3, 2021

The level of antibodies needed to provide protection isn’t known.

We are two years into what is billed as the worst epidemic to hit mankind with the main emphasis being a “vaccine”. The greatest medical minds (Fauci and Gates) have been on the “case”.

Now we are told there is no way to measure antibody levels due to Covid NATURAL immunity NOR FROM VACCINES. It makes me wonder how vaccine developers can measure anything antibody related.

This is literally unbelievable. Either the greatest 21st century medical minds (like Fauci and Gates) are inept or we just aren’t meant to know.

Then again, when the vaccinated can still get covid, can still transmit and are encouraged to wear a mask after being told the vaccine was a passport to no mask, it isn’t that hard to believe.

Don’t worry about it, by all means don’t think about it, just obey or you won’t get to go to the big game.

Adrianna Rodriguez USA TODAY People would like to know whether their COVID-19 vaccine is protective enough or a previous infection will keep them safe. Experts warned that taking an antibody test isn’t a good way to find out.

The tests were designed to show whether someone was recently infected with the coronavirus – not whether they have enough immune soldiers to prevent an infection.

The level of antibodies needed to provide protection isn’t known. There are nearly 90 different antibody tests on the market, most of which measure something slightly different.

Taking a test could give people a false sense of security, health experts said, or a load of unnecessary anxiety.

‘(Antibody tests) were never developed and designed to detect or tell us anything about vaccine-induced protective immunity,’ said Dr. Elitza Theel, director of the Infectious Diseases Serology Laboratory at the Mayo Clinic.

The Centers for Disease Control and Prevention and the Food and Drug Administration recommend against using antibody tests to assess immunity after COVID-19 vaccination.

As of Aug. 18, the FDA authorized nearly 90 different antibody tests to detect previous SARS-CoV-2 infection. Each test varies in which antibodies it detects, how well it detects them and how it reports results.

‘There are so many antibody tests out there that look for antibodies to different antigens,’ Theel said. ‘Their performance characteristics differ … there’s a lot of variability.’

A test’s sensitivity is its ability to recognize antibodies from the virus that causes COVID-19. Antibody tests can range from 85% to 99% sensitivity. Tests vary in specificity, which shows how likely a positive result is accurate.

Not all of them look for the same antibodies. Some tests look for antibodies created from a part of the virus called the nucleocapsid protein.

These antibodies serve only as a marker of previous infection and don’t provide any kind of protection against the virus, said Dr. Reynold Panettieri, professor of medicine at Robert Wood Johnson Medical School in New Brunswick, New Jersey.

‘It’s like a smoking gun,’ he said. ‘The bullet is the virus, the smoke from the gun is the nucleocapsid … all it (says) is you’ve gotten an exposure, but it’s not going to help you prevent infection.’

Only antibodies that prevent the virus from entering a cell provide protection from infection.

The COVID-19 vaccines help the body create antibodies to only the spike protein, which means people who have been vaccinated but not previously infected will show a negative result to a test that detects only antibodies from the nucleocapsid protein.

Some tests specifically test antibodies to the spike protein, but not all antibodies are protective.

Protective antibodies bind to the virus’s spike protein ACE2 receptor and prevent the virus from entering the cell.

‘They bind to the virus in a way that they neutralize its ability to infect the cell,’ Theel said.

Non-neutralizing antibodies may bind to other parts of the spike protein and have no effect on virus entry. Most tests don’t differentiate between the two types of antibodies.

A test that yields no spike protein antibodies doesn’t necessarily mean a person is unprotected from the virus, said Dr. Daniel Kuritzkes, chief of the division of infectious disease at Brigham and Women’s Hospital.

The body has experience producing those antibodies from the vaccine, he said. Even though there aren’t any detectable at the moment of testing, the body can quickly produce them again if it encounters the virus.

‘With any vaccine, the response you measure in the blood is going to decrease over time after vaccination because the body isn’t being constantly exposed to the foreign protein,’ Kuritzkes said. ‘But if they encounter the virus, the body can very rapidly have a recall, or a memory, response that is able to basically rush to the scene of infection and contain it.’

Even if all commercial tests were able to detect neutralizing antibodies from COVID-19 vaccines, health experts said, immunity would not be guaranteed as it’s unclear what levels ensure protection.

‘One of the biggest challenges and the reason why it’s not recommended to do post-vaccination antibody testing is because we still don’t have a defined correlate of protection,’ Theel said. ‘The higher number, the more antibodies you have. But what number is clinically significant and associated with protection? We can’t say, yet.’

Measuring antibodies captures only one part of the immune system, Theel said.

T-cells are one of the most important players in cellular immunity. Whereas protective neutralizing antibodies bind to the spike protein to prevent the virus from entering the cell, T-cells search and destroy infected cells where the virus reproduces.

The FDA authorized a test that detects a T-cell immune response to SARS-CoV-2 in March, but it’s not widely available.

‘So it would be a mistake for someone to measure an antibody response five or six months after the vaccine as not having immunity because your T-cell response is going to peak at that time, (and) it’s going to be more robust in generating immunity,’ Panettieri said.

Kuritzkes said Americans shouldn’t depend on antibody tests to assess immunity after COVID-19 vaccination, but there are a few exceptions. One includes people who have an immunocompromising condition or take immune suppressing medications.

If a spike protein antibody test yields no antibodies in a person who has a compromised immune system a month after getting fully vaccinated, it’s safer to assume that person did not build a sufficient immune response from the vaccine.

‘In that situation, people need to be concerned that they may be susceptible to COVID-19 and should continue to take precautions such as wearing masks when they’re out and about and avoid large gatherings,’ Kuritzkes said.

Health and patient safety coverage at USA TODAY is made possible in part by a grant from the Masimo Foundation for Ethics, Innovation and Competition in Healthcare. The Masimo Foundation does not provide editorial input. Most tests on market measure something slightly different

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UK to roll out antibody testing, planning ‘antibody certificates’ | Coronavirus pandemic News | Al Jazeera

Posted by M. C. on May 22, 2020

The level of immunity remains a mystery, wrote Nature’s editorial board. Tests are unreliable, the volume of testing needed is unfeasible and the threats to privacy and marginalised groups who would likely face even greater scrutiny all mean that immunity passports are a bad idea, they wrote.

Comrade, minor details like these will not stop the state.

Around one in six people in London and one in 20 elsewhere in England have already had the coronavirus, the United Kingdom’s Health Secretary Matt Hancock said, as he announced plans for “antibody certificates”.

Data gathered from an antibody surveillance study suggests 17 percent of people in London and around five percent of people across England have tested positive for antibodies to coronavirus, he told the daily Downing Street briefing.

This news comes as the government agreed to a deal with pharmaceutical firms Roche and Abbott for more than 10 million antibody tests, to see if people have had COVID-19.

They will first be offered to health and social care staff as well as patients and care home residents.

UK’s divided response: Varied messages across four nations [2:43]

The tests are not without their critics. Germany, one of the first countries to order millions of tests from Swiss drug giant Roche, said it would not use them until they had been debated by the country’s top ethicists.

Concern remains about how the issuing of “antibody passports” could lead to a two-tier society, with some people continuing to be locked down at home while others move about freely with life beginning to return to normal.

“In our view, any documentation that limits individual freedoms on the basis of biology risks becoming a platform for restricting human rights, increasing discrimination and threatening – rather than protecting – public health,” read an editorial comment in top science journal Nature.

The level of immunity remains a mystery, wrote Nature’s editorial board. Tests are unreliable, the volume of testing needed is unfeasible and the threats to privacy and marginalised groups who would likely face even greater scrutiny all mean that immunity passports are a bad idea, they wrote.

The UK government is, however, seemingly pressing on regardless, and also arranging supplies for the devolved administrations of Wales, Scotland and Northern Ireland, with each part of the UK deciding how to use its test allocation.

Syrian refugee’s message to Boris Johnson [1:54]

While it remains unclear what level of immunity people develop once they have had COVID-19, some experts hope a degree of immunity lasts for at least a year or two.

However, having antibodies does not automatically mean a person will not pass the virus onto somebody else.

Hancock said: “This is an important milestone and it represents further progress in our national testing programme. Knowing you have these antibodies will help us to understand in the future if you are at lower risk of catching coronavirus, dying from coronavirus and of transmitting coronavirus.”

Testing times

Hancock also announced a trial of a rapid 20-minute test to tell people if they currently have COVID-19 following criticisms that people have been waiting days or weeks for test results.

Accident and emergency hospital departments, general-practitioner testing hubs and care homes in Hampshire will all trial the new test, which will be used on up to 4,000 people.

The test does not need to be sent off to a lab and will be rolled out more widely if it is shown to be effective, Hancock said.

Can apps put coronavirus in check? | Inside Story [24:42]

Before the press briefing, Downing Street announced a U-turn on the National Health Service surcharge, saying overseas health and care staff would be exempted from the fee levied on migrants to pay for the NHS.

It came after mounting pressure on Prime Minister Boris Johnson from senior Tories, with former party chairman Lord Patten calling the charge “appalling” and “monstrous”.

Labour leader Sir Keir Starmer, who urged the prime minister in the Commons on Wednesday to scrap the charge, said: “Boris Johnson is right to have U-turned and backed our proposal to remove the NHS charge for health professionals and care workers.

“This is a victory for common decency and the right thing to do. We cannot clap our carers one day and then charge them to use our NHS the next.”

The decision came a day after another U-turn, when the government extended a scheme offering indefinite leave to remain in the UK to the families of all immigrant NHS staff who die as a result of contracting coronavirus.


At the daily press briefing, Hancock said certificates were being looked at for people who test positive for coronavirus antibodies.

Key workers at risk: UK companies accused of overlooking safety [2:27]

He said: “It’s not just about the clinical advances that these tests can bring.

“It’s that knowing that you have these antibodies will help us to understand more in the future if you are at lower risk of catching coronavirus, of dying from coronavirus and of transmitting coronavirus.

“We’re developing this critical science to know the impact of a positive antibody test and to develop the systems of certification to ensure people who have positive antibodies can be given assurances of what they can safely do.”

Meanwhile, England’s chief medical officer Professor Chris Whitty told the briefing the total number of deaths from all causes was now down to the rate in an average winter.

He said “All-cause mortality has come down at the same time as the COVID deaths have come down, and it is now at roughly the rate it is at in an average winter.

“So, we are essentially having a winter in health terms, in terms of mortality, but in late spring and early summer.”

Prof Whitty also said care home deaths had peaked and have now come down.

On the test, track and trace strategy, Hancock sought to play down the importance of the delayed app in the contact tracing process.

He had originally said the app would be rolled out by mid-May, but it has now been delayed by several weeks.

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Antibody Testing: Proves We’ve Been Had!

Posted by M. C. on May 14, 2020

There is simply no other way to state this.

Nearly everything we’ve been told about models, rates of infection, deaths, and recoveries was inaccurate.

I’m not here to argue that it was malfeasance or ignorance — both are unacceptable. But the one thing that Governor Andrew Cuomo’s stunning announcement made clear on Thursday is that there are some pretty shocking — and what should be — reassuring truths.

Cuomo announced that antibody testing in New York state, which only began four days previous, was already demonstrating that at minimum 13.9% of New Yorkers, had COVID-19 late stage antibodies.

The implication of this is a shockwave to the system.

With a population of 19,540,500 the findings point out that over 2,500,000 New Yorkers had the virus and have recovered. Keep in mind that as of this writing that only 263,000 New Yorkers have currently confirmed cases. Also as of this writing New York has reported 19,543 fatalities.

We’ve been told that the true death rate is 7.4% in New York. We were told there would be hundreds of thousands dead. We were told that this was worse than the flu, which has still recorded more deaths to date in this past flu season—even though the CDC instructed medical personnel to start counting influenza, heart disease, pulmonary, respiratory, drug overdose, and possibly even car crash deaths as COVID-19 deaths.

We were told that we had to upend an economy, go into solitary confinement, and divorce ourselves from normal life because this would rage beyond any previous pandemic. We were told that this virus with 846,000 current confirmed cases was worse than the H1N1 that broke out on Obama’s watch that infected 60,000,000 people. (We were conveniently not told that Obama had authorized $3.7 million U.S. tax dollars to be used at the Wuhan Institute of Virology to utilize corona viruses in bats in 2015 — but that’s yet another deception of omission.)

But none of these “truths” turned out to be so.

The death rate in New York State isn’t 7.4%, it is actually .75%. The recently ended influenza season numbers from the CDC indicate possibly 56,000,000 cases of flu, 740,000 hospitalizations, and 62,000 deaths. Under the current count from the Johns Hopkins Dashboard in this five month stretch CoVid19 has racked up 845,959 confirmed cases, 122,000 hospitalizations and 46,972 deaths.

A couple of other observations are extremely relevant. To begin with the flu — which has no vaccine but rather a randomized version of a shot designed to help develop antibodies to fight the version of the flu that “smart people” *think* will be the primary version that particular year — has remedies that physicians prescribe in primary care on an as needed basis. So we’re not accustomed to thinking that the flu is this deadly killer that all of life must be shut down to prevent. CoVid19 had no known treatments at the beginning of the breakout, and for political reasons—and possibly financially incentivized ones to boot—the most effective treatment for CoVid19 became a political football. Even the supposed “negative” trials that were reported on this past weekend, had cherry picked subjects that were mostly late stage victims of the virus. As Dr. Vladimir Zelenko pointed out on my show this week, doing so created the negative outcomes “purposefully & by design.” When used under a physician’s care, in the primary care basis, and early on after testing or onset of symptoms, the hydroxycholoroquine, azithromycin, & zinc cocktail reduced the rates of deaths and long term infectious stages. Zelenko’s numbers to date: 1,450 patients treated, two deaths, four ventilator cases (all fully recovered,) and all others recovered. Zelenko and other physicians using the treatment are releasing the world’s largest Meta-study to date within the next few days that will examine more than 2,000 confirmed cases.

The antibody numbers from Cuomo also scream one other harsh reality. The virus was in America long before January.

No thanks to the Communist Chinese Party — who bear the sole responsibility for every American who died from CoVid19 — the infection made its way to American sooner than we had believed. With three flights a day from Wuhan to New York’s John F. Kennedy airport alone the virus was being imported faster than understood.

Since going into national lockdown we’ve also failed one other key component of recovery from this virus—herd immunity. We’ve developed not nearly enough of it. For if 2.5 million New Yorkers were able to fight it off without any treatment at all—unaware they even had it—how much more immunity did we miss out on creating by simply sheltering everyone in place?

We are well on our way to a vaccine. We’ve also got a $12 treatment with the hydroxychloroquine cocktail that has smashed Brazil’s fatality rate by 95%.

Most importantly we’ve got millions upon millions of Americans who have been exposed to CoVid19 and who now have the late stage antibodies that demonstrate immunity.

It is time to acknowledge these facts, draw the necessary conclusions they lead us to, make changes for the benefit of the American people (for once), and end this nightmare.

Thank you Governor Cuomo for acknowledging it, now let’s go!

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